Ro 25-1392 [Ligand Id: 2276] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241] | ||||||||
| GtoPdb | inhibition of [125I]-VIP binding to CHO cells stably expressing the recombinant receptor | - | 5.5 | pKi | >3000 | nM | Ki | J Pharmacol Exp Ther (1997) 281: 629-33 [PMID:9152366] |
| GtoPdb | stimulation of cyclic AMP formation in CHO cells stably expressing the recombinant receptor | - | 6 | pEC50 | >1000 | nM | EC50 | J Pharmacol Exp Ther (1997) 281: 629-33 [PMID:9152366] |
| VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587] | ||||||||
| GtoPdb | inhibition of [125I]-VIP binding to CHO cells stably expressing the recombinant receptor | - | 8 | pKi | 9.6 | nM | Ki | J Pharmacol Exp Ther (1997) 281: 629-33 [PMID:9152366] |
| GtoPdb | stimulation of cyclic AMP formation in CHO cells stably expressing the recombinant receptor | - | 8.5 | pEC50 | 3 | nM | EC50 | J Pharmacol Exp Ther (1997) 281: 629-33 [PMID:9152366] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
