ChEMBL ligand: CHEMBL420762 (Mozavaptan, Mozavaptane)
OT receptor/Oxytocin receptor in Human [ChEMBL: CHEMBL2049] [GtoPdb: 369] [UniProtKB: P30559] There should be some charts here, you may need to enable JavaScript!
V1A receptor/Vasopressin V1a receptor in Human [ChEMBL: CHEMBL1889] [GtoPdb: 366] [UniProtKB: P37288] V1A receptor/Vasopressin V1a receptor in Rat [ChEMBL: CHEMBL2868] [GtoPdb: 366] [UniProtKB: P30560] There should be some charts here, you may need to enable JavaScript!
V2 receptor/Vasopressin V2 receptor in Human [ChEMBL: CHEMBL1790] [GtoPdb: 368] [UniProtKB: P30518] V2 receptor/Vasopressin V2 receptor in Rat [ChEMBL: CHEMBL3766] [GtoPdb: 368] [UniProtKB: Q00788] There should be some charts here, you may need to enable JavaScript!
V1B receptor in Human [GtoPdb: 367] [UniProtKB: P47901] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
OT receptor/Oxytocin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2049] [GtoPdb: 369] [UniProtKB: P30559]
ChEMBL	Binding affinity to oxytocin receptor	B	6.18	pKi	660	nM	Ki	J Med Chem (2012) 55: 8588-8602 [PMID:22984902]
V1A receptor/Vasopressin V1a receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1889] [GtoPdb: 366] [UniProtKB: P37288]
ChEMBL	Binding affinity to vasopressin V1a receptor	B	6.71	pKi	195	nM	Ki	J Med Chem (2012) 55: 8588-8602 [PMID:22984902]
GtoPdb	-	-	7.1	pKi	-	-	-	Br J Pharmacol (1998) 125: 1463-70 [PMID:9884074]; Endocrinology (1997) 138: 4109-22 [PMID:9322919]; J Pharmacol Exp Ther (1998) 287: 860-7 [PMID:9864265]
V1A receptor/Vasopressin V1a receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2868] [GtoPdb: 366] [UniProtKB: P30560]
GtoPdb	-	-	6.3	pKi	-	-	-	J Pharmacol Exp Ther (1998) 287: 860-7 [PMID:9864265]
ChEMBL	Displacement of [3H]AVP from AVP-V1a receptor binding site in rat liver	B	5.85	pIC50	1400	nM	IC50	J Med Chem (1996) 39: 3547-3555 [PMID:8784453]
V2 receptor/Vasopressin V2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1790] [GtoPdb: 368] [UniProtKB: P30518]
ChEMBL	Binding affinity to vasopressin V2 receptor	B	8.01	pKi	9.7	nM	Ki	J Med Chem (2012) 55: 8588-8602 [PMID:22984902]
ChEMBL	Concentration which inhibit [3H]AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%	B	8.03	pKi	9.42	nM	Ki	J Med Chem (2000) 43: 4388-4397 [PMID:11087564]
GtoPdb	-	-	8.1	pKi	-	-	-	Br J Pharmacol (1998) 125: 1463-70 [PMID:9884074]; Endocrinology (1997) 138: 4109-22 [PMID:9322919]; J Pharmacol Exp Ther (1998) 287: 860-7 [PMID:9864265]; Kidney Int (2000) 58: 1613-22 [PMID:11012895]; J Biol Chem (1998) 273: 29462-8 [PMID:9792651]
ChEMBL	Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cells	B	6.3	pIC50	500	nM	IC50	J Med Chem (1981) 24: 496-499 [PMID:7241506]
V2 receptor/Vasopressin V2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3766] [GtoPdb: 368] [UniProtKB: Q00788]
GtoPdb	-	-	8.2	pKi	-	-	-	J Pharmacol Exp Ther (1998) 287: 860-7 [PMID:9864265]; J Biol Chem (1998) 273: 29462-8 [PMID:9792651]
ChEMBL	Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medulla	B	6.52	pIC50	300	nM	IC50	J Med Chem (1981) 24: 496-499 [PMID:7241506]
ChEMBL	Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney	B	7.92	pIC50	12	nM	IC50	J Med Chem (1996) 39: 3547-3555 [PMID:8784453]
V1B receptor in Human [GtoPdb: 367] [UniProtKB: P47901]
GtoPdb	-	-	4.8	pKi	-	-	-	Endocrinology (1997) 138: 4109-22 [PMID:9322919]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]