urotensin II-related peptide [Ligand Id: 2156] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL437110 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| UT receptor/Urotensin II receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3764] [GtoPdb: 365] [UniProtKB: Q9UKP6] | ||||||||
| GtoPdb | - | - | 9.6 | pKd | 0.24 | nM | Kd |
Peptides (2008) 29: 809-12 [PMID:17628210]; J Neurochem (2008) 107: 361-74 [PMID:18710417] |
| ChEMBL | Displacement of [125I]human urotensin-2 from human GPR14 transfected in CHO cells | B | 6.58 | pKi | 263.03 | nM | Ki | J Med Chem (2006) 49: 7234-7238 [PMID:17125276] |
| GtoPdb | - | - | 8.6 | pIC50 | - | - | - | Biochem Biophys Res Commun (2003) 310: 860-8 [PMID:14550283] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
