[Leu31,Pro34]NPY [Ligand Id: 1545] activity data from GtoPdb

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  • Y1 receptor in Human [GtoPdb: 305] [UniProtKB: P25929]
  • Y1 receptor in Rat [GtoPdb: 305] [UniProtKB: P21555]
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  • Y2 receptor in Human [GtoPdb: 306] [UniProtKB: P49146]
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  • Y4 receptor in Human [GtoPdb: 307] [UniProtKB: P50391]
  • Y4 receptor in Mouse [GtoPdb: 307] [UniProtKB: Q61041]
  • Y4 receptor in Rat [GtoPdb: 307] [UniProtKB: Q63447]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Y1 receptor in Human [GtoPdb: 305] [UniProtKB: P25929]
GtoPdb - - 7.1 pEC50 78.7 nM EC50 Br J Pharmacol (1995) 116: 2673-8 [PMID:8590988]
Y1 receptor in Rat [GtoPdb: 305] [UniProtKB: P21555]
GtoPdb - - 10.6 pKi - - - Peptides (1997) 18: 397-401 [PMID:9145427]
GtoPdb - - 8.6 pIC50 - - - Mol Pharmacol (1992) 41: 817-21 [PMID:1316999]
Y2 receptor in Human [GtoPdb: 306] [UniProtKB: P49146]
GtoPdb - - 6.2 pKi - - - J Biol Chem (1995) 270: 26758-61 [PMID:7592910]
Y4 receptor in Human [GtoPdb: 307] [UniProtKB: P50391]
GtoPdb - - 7.7 pKi - - - J Biol Chem (1995) 270: 29123-8 [PMID:7493937]
Y4 receptor in Mouse [GtoPdb: 307] [UniProtKB: Q61041]
GtoPdb - - 9.5 pIC50 - - - FEBS Lett (1996) 381: 58-62 [PMID:8641440]
Y4 receptor in Rat [GtoPdb: 307] [UniProtKB: Q63447]
GtoPdb - - 8.3 pKi - - - Peptides (1997) 18: 609-12 [PMID:9210181]
GtoPdb - - 10.7 pKi - - - Peptides (1997) 18: 397-401 [PMID:9145427];
Proc Natl Acad Sci USA (1996) 93: 5111-5 [PMID:8643536];
Peptides (1997) 18: 609-12 [PMID:9210181]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.