compound 15 [PMID: 41769711] [Ligand Id: 14423] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| KRAS in Human [GtoPdb: 2824] [UniProtKB: P01116] | ||||||||
| GtoPdb | Determined in an assay measuring KRAS G12C alkylation in HCC1171 cells | - | 7.77 | pIC50 | 17 | nM | IC50 | J Med Chem (2026) : [PMID:41769711] |
| GtoPdb | KRAS G12C enzymatic inhibition determined in a SOS1-mediated nucleotide exchange assay | - | 9.28 | pIC50 | 0.53 | nM | IC50 | J Med Chem (2026) : [PMID:41769711] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
