lorigerlimab [Ligand Id: 14407] activity data from GtoPdb

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  • cytotoxic T-lymphocyte-associated protein 4 (CD152) in Human [GtoPdb: 2743] [UniProtKB: P16410]
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  • programmed cell death 1 (CD279) in Human [GtoPdb: 2760] [UniProtKB: Q15116]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cytotoxic T-lymphocyte-associated protein 4 (CD152) in Human [GtoPdb: 2743] [UniProtKB: P16410]
GtoPdb Measuring inhibition of B7-1 binding binding to CTLA-4 on Jurkat cells co-expressing PD-1 and CTLA-4 - 10.85 pEC50 0.01 nM EC50 Cell Rep Med (2020) 1: 100163 [PMID:33377134]
programmed cell death 1 (CD279) in Human [GtoPdb: 2760] [UniProtKB: Q15116]
GtoPdb Measuring inhibition of PD-L1 binding to PD-1 on Jurkat cells - 9.38 pEC50 0.42 nM EC50 Cell Rep Med (2020) 1: 100163 [PMID:33377134]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.