rosnilimab [Ligand Id: 14271] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| programmed cell death 1 (CD279) in Monkey [GtoPdb: 2760] | ||||||||
| GtoPdb | Binding affinity determined by SPR | - | 6.61 | pKd | 244 | nM | Kd | US20220235132A1. Pd-1 agonist and method of using same (2022) |
| programmed cell death 1 (CD279) in Human [GtoPdb: 2760] [UniProtKB: Q15116] | ||||||||
| GtoPdb | Binding affinity determined by SPR | - | 10.29 | pKd | 0.05 | nM | Kd | US20220235132A1. Pd-1 agonist and method of using same (2022) |
| GtoPdb | Potency determined in a competition binding assay displacing human PD-L1 | - | 6.3 | pIC50 | ~500 | nM | IC50 | US20220235132A1. Pd-1 agonist and method of using same (2022) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
