ChEMBL ligand: CHEMBL5284353
GPR52/Probable G-protein coupled receptor 52 in Human [ChEMBL: CHEMBL3297639] [GtoPdb: 108] [UniProtKB: Q9Y2T5] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
GPR52/Probable G-protein coupled receptor 52 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3297639] [GtoPdb: 108] [UniProtKB: Q9Y2T5]
ChEMBL	Agonist activity at human GPR52 expressed in HEK293F assessed as cAMP accumulation preincubated for 30 mins followed by cAMP detection reagent and measured after 1 hr by HTRF analysis	B	7.5	pEC50	31.62	nM	EC50	ACS Med Chem Lett (2023) 14: 499-505 [PMID:37077397]
GtoPdb	Potency determined in a cAMP accumulation assay in HEK293F cells expressing hGPR52	-	7.56	pEC50	27.5	nM	EC50	ACS Med Chem Lett (2023) 14: 499-505 [PMID:37077397]
ChEMBL	Agonist activity at human GPR52 expressed in HEK293F assessed as cAMP accumulation preincubated for 30 mins followed by cAMP detection reagent and measured after 1 hr by HTRF analysis	B	7.56	pEC50	27.5	nM	EC50	ACS Med Chem Lett (2023) 14: 499-505 [PMID:37077397]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]