NST-628 [Ligand Id: 13370] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056] | ||||||||
| GtoPdb | Binding affinity of ligand for the the MEK1-BRAF binary complex in vitro, determined by SPR assay. | - | 7.3 | pKd | 50.5 | nM | Kd | Cancer Discov (2024) 14: 1190-1205 [PMID:38588399] |
| Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049] | ||||||||
| GtoPdb | Binding affinity of ligand for the the MEK1-CRAF binary complex in vitro, determined by SPR assay. | - | 7.41 | pKd | 38.6 | nM | Kd | Cancer Discov (2024) 14: 1190-1205 [PMID:38588399] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
