sinefungin [Ligand Id: 13317] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1214186
  • CoV Non-structural protein 16 in SARS-CoV [GtoPdb: 3276]
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  • CoV 2'-O-methyltransferase in SARS-CoV-2 [GtoPdb: 3277]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CoV Non-structural protein 16 in SARS-CoV [GtoPdb: 3276]
GtoPdb - - 6.13 pIC50 736 nM IC50 Nat Commun (2020) 11: 3717 [PMID:32709887]
CoV 2'-O-methyltransferase in SARS-CoV-2 [GtoPdb: 3277]
GtoPdb - - 5.47 pIC50 3400 nM IC50 SLAS Discov (2021) 26: 757-765 [PMID:33874769]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]