asandeutertinib [Ligand Id: 13201] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Inhibition of phosphorylation of WT EGFR in LoVo cells | - | 8.6 | pIC50 | 2.53 | nM | IC50 | US10414756B2. 2-(2,4,5-substituted aniline) pyrimidine derivative, pharmaceutical composition and use thereof (2019) |
| GtoPdb | Inhibition of phosphorylation of EGFR in PC9 cells with Exon19 deletion EGFR | - | 10.7 | pIC50 | 0.02 | nM | IC50 | US10414756B2. 2-(2,4,5-substituted aniline) pyrimidine derivative, pharmaceutical composition and use thereof (2019) |
| GtoPdb | Inhibition of phosphorylation of EGFR in NCI-H1975 cells with L858R/T790M EGFR double mutant | - | 10.92 | pIC50 | 0.01 | nM | IC50 | US10414756B2. 2-(2,4,5-substituted aniline) pyrimidine derivative, pharmaceutical composition and use thereof (2019) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
