ChEMBL ligand: CHEMBL3823931
patatin like domain 2, triacylglycerol lipase/Patatin-like phospholipase domain-containing protein 2 in Human [ChEMBL: CHEMBL3822353] [GtoPdb: 3253] [UniProtKB: Q96AD5] Patatin-like phospholipase domain-containing protein 2 in Mouse [ChEMBL: CHEMBL3425391] [UniProtKB: Q8BJ56] There should be some charts here, you may need to enable JavaScript!
histone deacetylase 6/Protein deacetylase HDAC6 in Human [ChEMBL: CHEMBL1865] [GtoPdb: 2618] [UniProtKB: Q9UBN7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
patatin like domain 2, triacylglycerol lipase/Patatin-like phospholipase domain-containing protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3822353] [GtoPdb: 3253] [UniProtKB: Q96AD5]
GtoPdb	-	-	6.15	pIC50	700	nM	IC50	Nat Chem Biol (2013) 9: 785-7 [PMID:24096302]
ChEMBL	Inhibition of ATGL (unknown origin) overexpressed in Escherichia coli XL-1 cells using [9,10-3H(N)]triolein as substrate incubated for 60 mins by liquid scintillation counting method	B	6.15	pIC50	700	nM	IC50	Eur J Med Chem (2016) 118: 290-298 [PMID:27155760]
Patatin-like phospholipase domain-containing protein 2 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3425391] [UniProtKB: Q8BJ56]
ChEMBL	Inhibition of murine ATGL expressed in COS-7 cells	B	5.3	pIC50	<5000	nM	IC50	Bioorg Med Chem (2020) 28: 115610-115610 [PMID:32690265]
ChEMBL	Inhibition of recombinant murine ATGL expressed in Escherichia coli XL-1 lysates	B	6.15	pIC50	700	nM	IC50	Bioorg Med Chem (2020) 28: 115610-115610 [PMID:32690265]
histone deacetylase 6/Protein deacetylase HDAC6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1865] [GtoPdb: 2618] [UniProtKB: Q9UBN7]
ChEMBL	Determination of IC50 values for inhibition of enzymatic assay of human HDAC6 with custom peptide substrate	B	5.79	pIC50	1613	nM	IC50	HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators

ChEMBL data shown on this page come from version 37:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]