LUNA18 [Ligand Id: 12931] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| KRAS in Human [GtoPdb: 2824] [UniProtKB: P01116] | ||||||||
| GtoPdb | Binding affinity for KRASG12D | - | 10.37 | pKd | 0.04 | nM | Kd | J Am Chem Soc (2023) 145: 16610-16620 [PMID:37463267] |
| GtoPdb | Inhibition of AsPC-1 cell (pancreatic cancer cells with KRASG12D mutation) proliferation | - | 8.85 | pIC50 | 1.4 | nM | IC50 | J Am Chem Soc (2023) 145: 16610-16620 [PMID:37463267] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
