TRULI [Ligand Id: 12663] activity data from GtoPdb

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  • large tumor suppressor kinase 1 in Human [GtoPdb: 1515] [UniProtKB: O95835]
Created with Highcharts 10.3.3ValuesChart context menularge tumor suppressor kinase 1pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • large tumor suppressor kinase 2 in Human [GtoPdb: 1516] [UniProtKB: Q9NRM7]
Created with Highcharts 10.3.3ValuesChart context menularge tumor suppressor kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
large tumor suppressor kinase 1 in Human [GtoPdb: 1515] [UniProtKB: O95835]
GtoPdb LATS1 inhibition at 10 μM ATP - 9.7 pIC50 0.2 nM IC50 Nat Commun (2021) 12: 3100 [PMID:34035288]
large tumor suppressor kinase 2 in Human [GtoPdb: 1516] [UniProtKB: Q9NRM7]
GtoPdb LATS2 inhibition at 10 μM ATP - 9.7 pIC50 0.2 nM IC50 Nat Commun (2021) 12: 3100 [PMID:34035288]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.