BI-847325 [Ligand Id: 12661] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| large tumor suppressor kinase 1 in Human [GtoPdb: 1515] [UniProtKB: O95835] | ||||||||
| GtoPdb | - | - | 6.2 | pKd | 630 | nM | Kd | Science (2017) 358: [PMID:29191878] |
| aurora kinase A in Human [GtoPdb: 1936] [UniProtKB: O14965] | ||||||||
| GtoPdb | - | - | 7.6 | pIC50 | 25 | nM | IC50 | Mol Cancer Ther (2016) 15: 2388-2398 [PMID:27496137] |
| aurora kinase C in Human [GtoPdb: 1938] [UniProtKB: Q9UQB9] | ||||||||
| GtoPdb | - | - | 7.82 | pIC50 | 15 | nM | IC50 | Mol Cancer Ther (2016) 15: 2388-2398 [PMID:27496137] |
| mitogen-activated protein kinase kinase 1 in Human [GtoPdb: 2062] [UniProtKB: Q02750] | ||||||||
| GtoPdb | - | - | 7.6 | pIC50 | 25 | nM | IC50 | Mol Cancer Ther (2016) 15: 2388-2398 [PMID:27496137] |
| mitogen-activated protein kinase kinase 2 in Human [GtoPdb: 2063] [UniProtKB: P36507] | ||||||||
| GtoPdb | - | - | 8.4 | pIC50 | 4 | nM | IC50 | Mol Cancer Ther (2016) 15: 2388-2398 [PMID:27496137] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
