ACT-777991 [Ligand Id: 12584] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| CXCR3 in Human [GtoPdb: 70] [UniProtKB: P49682] | ||||||||
| GtoPdb | Binding affinity determined in an association assay using [3H]ACT-777991 | - | 8.34 | pKd | 4.6 | nM | Kd | J Med Chem (2023) 66: 4179-4196 [PMID:36883854] |
| GtoPdb | Antagonism of CXCL9-mediated CXCR3 activation in a calcium signaling assay | - | 8.48 | pIC50 | 3.3 | nM | IC50 | J Med Chem (2023) 66: 4179-4196 [PMID:36883854] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
