compound 7 [Nguyen et al., 2023] [Ligand Id: 12485] activity data from GtoPdb

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  • activin A receptor type 1 in Human [GtoPdb: 1785] [UniProtKB: Q04771]
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  • fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
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  • fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
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  • fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607]
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  • fibroblast growth factor receptor 4 in Human [GtoPdb: 1811] [UniProtKB: P22455]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
activin A receptor type 1 in Human [GtoPdb: 1785] [UniProtKB: Q04771]
GtoPdb - - 6.03 pIC50 930 nM IC50 ACS Medicinal Chemistry Letters (2023) 14: 312–318
fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
GtoPdb - - 7.05 pIC50 89 nM IC50 ACS Medicinal Chemistry Letters (2023) 14: 312–318
fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
GtoPdb - - 8.28 pIC50 5.2 nM IC50 ACS Medicinal Chemistry Letters (2023) 14: 312–318
fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607]
GtoPdb - - 8.25 pIC50 5.6 nM IC50 ACS Medicinal Chemistry Letters (2023) 14: 312–318
fibroblast growth factor receptor 4 in Human [GtoPdb: 1811] [UniProtKB: P22455]
GtoPdb - - 6.45 pIC50 351 nM IC50 ACS Medicinal Chemistry Letters (2023) 14: 312–318

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.