JBI-589 [Ligand Id: 12481] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| peptidyl arginine deiminase 4 in Human [GtoPdb: 2877] [UniProtKB: Q9UM07] | ||||||||
| GtoPdb | Inhibition of PADI4 enzymatic activity in vitro, in a biochemical assay measuring ammonia release | - | 6.91 | pIC50 | 122 | nM | IC50 | Sci Rep (2023) 13: 3189 [PMID:36823444] |
| GtoPdb | Measuring inhibition of histone citrullination in neutrophils | - | 7 | pIC50 | 100 | nM | IC50 | WO2022034616A1. Method and compound for use, in treating and/or preventing netosis (2022) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
