ChEMBL ligand: CHEMBL76447 (NSC-76751)
ABCG2/ATP-binding cassette sub-family G member 2 in Human [ChEMBL: CHEMBL5393] [GtoPdb: 792] [UniProtKB: Q9UNQ0] There should be some charts here, you may need to enable JavaScript!
ABCB1/P-glycoprotein 1 in Human [ChEMBL: CHEMBL4302] [GtoPdb: 768] [UniProtKB: P08183] There should be some charts here, you may need to enable JavaScript!
xanthine dehydrogenase/Xanthine dehydrogenase in Human [ChEMBL: CHEMBL1929] [GtoPdb: 2646] [UniProtKB: P47989] There should be some charts here, you may need to enable JavaScript!
TAS2R14 in Human [GtoPdb: 668] [UniProtKB: Q9NYV8] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ABCG2/ATP-binding cassette sub-family G member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5393] [GtoPdb: 792] [UniProtKB: Q9UNQ0]
ChEMBL	Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 staining	B	5.31	pIC50	4900	nM	IC50	Bioorg Med Chem (2011) 19: 2090-2102 [PMID:21354800]
ChEMBL	Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 staining	B	5.36	pIC50	4400	nM	IC50	Bioorg Med Chem (2011) 19: 2090-2102 [PMID:21354800]
GtoPdb	Inhibition of hBCRP expressed in MCF-7 MX cells	-	5.36	pIC50	4400	nM	IC50	Bioorg Med Chem (2011) 19: 2090-102 [PMID:21354800]
ABCB1/P-glycoprotein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4302] [GtoPdb: 768] [UniProtKB: P08183]
ChEMBL	TP_TRANSPORTER: inhibition of Daunorubicin efflux in NIH-3T3-G185 cells	F	4.94	pIC50	11500	nM	IC50	Chem Res Toxicol (2001) 14: 1596-1603 [PMID:11743742]
xanthine dehydrogenase/Xanthine dehydrogenase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1929] [GtoPdb: 2646] [UniProtKB: P47989]
ChEMBL	Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry	B	4	pIC50	>100000	nM	IC50	J Nat Prod (1998) 61: 71-76 [PMID:9461655]
TAS2R14 in Human [GtoPdb: 668] [UniProtKB: Q9NYV8]
GtoPdb	-	-	5.68	pEC50	2100	nM	EC50	Chem Biol Drug Des (2018) 91: 422-433 [PMID:28834122]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]