adrixetinib [Ligand Id: 12375] activity data from GtoPdb

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  • colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
Created with Highcharts 10.3.3ValuesChart context menucolony stimulating factor 1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • AXL receptor tyrosine kinase in Human [GtoPdb: 1835] [UniProtKB: P30530]
Created with Highcharts 10.3.3ValuesChart context menuAXL receptor tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • MER proto-oncogene, tyrosine kinase in Human [GtoPdb: 1837] [UniProtKB: Q12866]
Created with Highcharts 10.3.3ValuesChart context menuMER proto-oncogene, tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
GtoPdb - - 7 pKd <100 nM Kd US20210163448A1. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r (2021)
AXL receptor tyrosine kinase in Human [GtoPdb: 1835] [UniProtKB: P30530]
GtoPdb - - 7 pKd <100 nM Kd US20210163448A1. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r (2021)
MER proto-oncogene, tyrosine kinase in Human [GtoPdb: 1837] [UniProtKB: Q12866]
GtoPdb - - 7 pKd <100 nM Kd US20210163448A1. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r (2021)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.