compound 5i [PMID: 36542759] [Ligand Id: 12336] activity data from GtoPdb

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  • mitogen-activated protein kinase kinase kinase kinase 1 in Human [GtoPdb: 2085] [UniProtKB: Q92918]
Created with Highcharts 10.3.3ValuesChart context menumitogen-activated protein kinase kinase kinase kinase 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • mitogen-activated protein kinase kinase kinase kinase 3 in Human [GtoPdb: 2087] [UniProtKB: Q8IVH8]
Created with Highcharts 10.3.3ValuesChart context menumitogen-activated protein kinase kinase kinase kinase 3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mitogen-activated protein kinase kinase kinase kinase 1 in Human [GtoPdb: 2085] [UniProtKB: Q92918]
GtoPdb - - 9.1 pIC50 0.8 nM IC50 J Med Chem (2023) 66: 611-626 [PMID:36542759]
mitogen-activated protein kinase kinase kinase kinase 3 in Human [GtoPdb: 2087] [UniProtKB: Q8IVH8]
GtoPdb - - 7.09 pIC50 81 nM IC50 J Med Chem (2023) 66: 611-626 [PMID:36542759]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.