compound 61 [PMID: 36221183] [Ligand Id: 12224] activity data from GtoPdb

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  • ubiquitin specific peptidase 1 in Human [GtoPdb: 2428] [UniProtKB: O94782]
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  • OTU deubiquitinase, ubiquitin aldehyde binding 1 in Human [GtoPdb: 3208] [UniProtKB: Q96FW1]
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  • ubiquitin specific peptidase 8 in Human [GtoPdb: 3209] [UniProtKB: P40818]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ubiquitin specific peptidase 1 in Human [GtoPdb: 2428] [UniProtKB: O94782]
GtoPdb - - 5.86 pIC50 1370 nM IC50 J Med Chem (2022) 65: 13645-13659 [PMID:36221183]
OTU deubiquitinase, ubiquitin aldehyde binding 1 in Human [GtoPdb: 3208] [UniProtKB: Q96FW1]
GtoPdb - - 9.77 pIC50 0.17 nM IC50 J Med Chem (2022) 65: 13645-13659 [PMID:36221183]
ubiquitin specific peptidase 8 in Human [GtoPdb: 3209] [UniProtKB: P40818]
GtoPdb - - 9.55 pIC50 0.28 nM IC50 J Med Chem (2022) 65: 13645-13659 [PMID:36221183]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.