pifusertib [Ligand Id: 12084] activity data from GtoPdb

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  • AKT serine/threonine kinase 1 in Human [GtoPdb: 1479] [UniProtKB: P31749]
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  • AKT serine/threonine kinase 2 in Human [GtoPdb: 1480] [UniProtKB: P31751]
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  • AKT serine/threonine kinase 3 in Human [GtoPdb: 2286] [UniProtKB: Q9Y243]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
AKT serine/threonine kinase 1 in Human [GtoPdb: 1479] [UniProtKB: P31749]
GtoPdb - - 8.32 pIC50 4.8 nM IC50 Cancer Res (2014) 74: 4458-69 [PMID:24934808]
AKT serine/threonine kinase 2 in Human [GtoPdb: 1480] [UniProtKB: P31751]
GtoPdb - - 8.8 pIC50 1.6 nM IC50 Cancer Res (2014) 74: 4458-69 [PMID:24934808]
AKT serine/threonine kinase 3 in Human [GtoPdb: 2286] [UniProtKB: Q9Y243]
GtoPdb - - 7.36 pIC50 44 nM IC50 Cancer Res (2014) 74: 4458-69 [PMID:24934808]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.