secretin [Ligand Id: 1155] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| secretin receptor in Rat [GtoPdb: 252] [UniProtKB: P23811] | ||||||||
| GtoPdb | - | - | 9 | pKi | - | - | - | EMBO J (1991) 10: 1635-41 [PMID:1646711] |
| GtoPdb | Inhibition of [125I]Tyr25 secretin binding in membranes from CHO cells expressing recombinant receptor | - | 9 | pIC50 | 1 | nM | IC50 | Peptides (1997) 18: 1539-45 [PMID:9437714] |
| PAC1 receptor in Rat [GtoPdb: 370] [UniProtKB: P32215] | ||||||||
| GtoPdb | Inhibition of [125I]-Ac-His1-PACAP-27 binding in membranes from CHO cells expressing recombinant receptor | - | 4.5 | pIC50 | 30000 | nM | IC50 | Peptides (1997) 18: 1539-45 [PMID:9437714] |
| VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241] | ||||||||
| GtoPdb | inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor | - | 5 | pKi | >10000 | nM | Ki | Eur J Pharmacol (1996) 302: 207-14 [PMID:8791009] |
| GtoPdb | inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor | - | 5.8 | pIC50 | 1500 | nM | IC50 | Ann N Y Acad Sci (1998) 865: 247-52 [PMID:9928018] |
| GtoPdb | Inhibition of [125I]VIP binding in membranes from LoVo cells expressing recombinant receptor | - | 5.8 | pIC50 | 1500 | nM | IC50 | Peptides (1997) 18: 1539-45 [PMID:9437714] |
| VPAC1 receptor in Rat [GtoPdb: 371] [UniProtKB: P30083] | ||||||||
| GtoPdb | inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor | - | 6.5 | pIC50 | 300 | nM | IC50 | Ann N Y Acad Sci (1998) 865: 247-52 [PMID:9928018] |
| GtoPdb | Inhibition of [125I]VIP binding in membranes from CHO cells expressing recombinant receptor | - | 6.5 | pIC50 | 300 | nM | IC50 | Peptides (1997) 18: 1539-45 [PMID:9437714] |
| VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587] | ||||||||
| GtoPdb | inhibition of [125I]Ro25 1553 binding to membranes from CHO cells stably expressing the recombinant receptor | - | 5.3 | pIC50 | 5000 | nM | IC50 | Ann N Y Acad Sci (1998) 865: 247-52 [PMID:9928018] |
| GtoPdb | Inhibition of [125I]VIP binding in membranes from CHO cells expressing recombinant receptor | - | 5.3 | pIC50 | 5000 | nM | IC50 | Peptides (1997) 18: 1539-45 [PMID:9437714] |
| VPAC2 receptor in Rat [GtoPdb: 372] [UniProtKB: P35000] | ||||||||
| GtoPdb | inhibition of [125I]Ro25 1553 binding to membranes from CHO cells stably expressing the recombinant receptor | - | 4.5 | pIC50 | 30000 | nM | IC50 | Ann N Y Acad Sci (1998) 865: 247-52 [PMID:9928018] |
| GtoPdb | Inhibition of [125I]VIP binding in membranes from CHO cells expressing recombinant receptor | - | 4.5 | pIC50 | 30000 | nM | IC50 | Peptides (1997) 18: 1539-45 [PMID:9437714] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
