NS383 [Ligand Id: 11474] activity data from GtoPdb

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  • ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
Created with Highcharts 10.3.3ValuesChart context menuASIC1pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
Created with Highcharts 10.3.3ValuesChart context menuASIC3pKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
GtoPdb ASIC1a at pH6.5 - 6.4 pIC50 398 nM IC50 CNS Neurosci Ther (2016) 22: 135-45 [PMID:26663905]
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
GtoPdb at pH6.5 - 5.7 pIC50 1995 nM IC50 CNS Neurosci Ther (2016) 22: 135-45 [PMID:26663905]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.