tirzepatide [Ligand Id: 11429] activity data from GtoPdb

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  • GIP receptor in Human [GtoPdb: 248] [UniProtKB: P48546]
Created with Highcharts 10.3.3ValuesChart context menuGIP receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • GLP-1 receptor in Human [GtoPdb: 249] [UniProtKB: P43220]
Created with Highcharts 10.3.3ValuesChart context menuGLP-1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GIP receptor in Human [GtoPdb: 248] [UniProtKB: P48546]
GtoPdb - - 9.87 pKi 0.14 nM Ki Mol Metab (2018) 18: 3-14 [PMID:30473097]
GLP-1 receptor in Human [GtoPdb: 249] [UniProtKB: P43220]
GtoPdb - - 8.37 pKi 4.23 nM Ki Mol Metab (2018) 18: 3-14 [PMID:30473097]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.