LYS006 [Ligand Id: 11205] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Leukotriene A4 hydrolase in Human [GtoPdb: 1395] [UniProtKB: P09960] | ||||||||
| GtoPdb | Determined in human PBMC | - | 8.43 | pIC50 | 3.7 | nM | IC50 | J Med Chem (2021) 64: 1889-1903 [PMID:33592148] |
| GtoPdb | Inhibition of enzyme activity determined in a fluorescence assay using a 7-amino-4-methylcoumarin (AMC) arginine derivative (Arg-AMC) as a surrogate substrate for LTA4H. | - | 8.7 | pIC50 | 2 | nM | IC50 | WO2015092740A1. Heteroaryl butanoic acid derivatives as lta4h inhibitors (2015) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
