compound 8u [PMID: 31999451] [Ligand Id: 10682] activity data from GtoPdb

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  • indoleamine 2,3-dioxygenase 1 in Human [GtoPdb: 2829] [UniProtKB: P14902]
Created with Highcharts 10.3.3ValuesChart context menuindoleamine 2,3-dioxygenase 1pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • signal transducer and activator of transcription 3 in Human [GtoPdb: 2994] [UniProtKB: P40763]
Created with Highcharts 10.3.3ValuesChart context menusignal transducer and activator of transcription 3pKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
indoleamine 2,3-dioxygenase 1 in Human [GtoPdb: 2829] [UniProtKB: P14902]
GtoPdb Binding dissociation constant determined for recombinant human IDO1 by SPR analysis. - 7.1 pKd 80 nM Kd J Med Chem (2020) 63: 1544-1563 [PMID:31999451]
signal transducer and activator of transcription 3 in Human [GtoPdb: 2994] [UniProtKB: P40763]
GtoPdb Binding dissociation constant for human STAT3 determined by SPR analysis. - 6.28 pKd 530 nM Kd J Med Chem (2020) 63: 1544-1563 [PMID:31999451]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.