cilofexor [Ligand Id: 10644] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Farnesoid X receptor in Human [GtoPdb: 603] [UniProtKB: Q96RI1] | ||||||||
| GtoPdb | EC50 determined as the ability of cilofexor to modulate the interaction between the purified bacterial expressed FXR ligand binding domain (LBD) and a synthetic biotinylated peptide based on residues 676-700 of SRC1, in a TR-FRET assay. | - | 7.6 | pEC50 | <25 | nM | EC50 | US10485795B2. FXR (NR1H4) binding and activity modulating compounds (2019) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
