BAY-985 [Ligand Id: 10597] activity data from GtoPdb

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  • ribosomal protein S6 kinase A6 in Human [GtoPdb: 1530] [UniProtKB: Q9UK32]
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  • fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
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  • inhibitor of nuclear factor kappa B kinase subunit epsilon in Human [GtoPdb: 2040] [UniProtKB: Q14164]
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  • serine/threonine kinase 17a in Human [GtoPdb: 2214] [UniProtKB: Q9UEE5]
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  • TANK binding kinase 1 in Human [GtoPdb: 2237] [UniProtKB: Q9UHD2]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ribosomal protein S6 kinase A6 in Human [GtoPdb: 1530] [UniProtKB: Q9UK32]
GtoPdb - - 6.56 pIC50 276 nM IC50 J. Med. Chem. (2020) 63: 601-612 [PMID:31859507]
fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
GtoPdb - - 6.91 pIC50 123 nM IC50 J. Med. Chem. (2020) 63: 601-612 [PMID:31859507]
inhibitor of nuclear factor kappa B kinase subunit epsilon in Human [GtoPdb: 2040] [UniProtKB: Q14164]
GtoPdb - - 8.7 pIC50 2 nM IC50 J. Med. Chem. (2020) 63: 601-612 [PMID:31859507]
serine/threonine kinase 17a in Human [GtoPdb: 2214] [UniProtKB: Q9UEE5]
GtoPdb - - 6.51 pIC50 311 nM IC50 J. Med. Chem. (2020) 63: 601-612 [PMID:31859507]
TANK binding kinase 1 in Human [GtoPdb: 2237] [UniProtKB: Q9UHD2]
GtoPdb Inhibition at low ATP concentration. - 8.7 pIC50 2 nM IC50 J. Med. Chem. (2020) 63: 601-612 [PMID:31859507]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.