BAY-985 [Ligand Id: 10597] activity data from GtoPdb

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  • ribosomal protein S6 kinase A6 in Human [GtoPdb: 1530] [UniProtKB: Q9UK32]
Created with Highcharts 10.3.3ValuesChart context menuribosomal protein S6 kinase A6pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
Created with Highcharts 10.3.3ValuesChart context menufms related receptor tyrosine kinase 3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • inhibitor of nuclear factor kappa B kinase subunit epsilon in Human [GtoPdb: 2040] [UniProtKB: Q14164]
Created with Highcharts 10.3.3ValuesChart context menuinhibitor of nuclear factor kappa B kinase subunit epsilonpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • serine/threonine kinase 17a in Human [GtoPdb: 2214] [UniProtKB: Q9UEE5]
Created with Highcharts 10.3.3ValuesChart context menuserine/threonine kinase 17apKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • TANK binding kinase 1 in Human [GtoPdb: 2237] [UniProtKB: Q9UHD2]
Created with Highcharts 10.3.3ValuesChart context menuTANK binding kinase 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ribosomal protein S6 kinase A6 in Human [GtoPdb: 1530] [UniProtKB: Q9UK32]
GtoPdb - - 6.56 pIC50 276 nM IC50 J Med Chem (2020) 63: 601-612 [PMID:31859507]
fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
GtoPdb - - 6.91 pIC50 123 nM IC50 J Med Chem (2020) 63: 601-612 [PMID:31859507]
inhibitor of nuclear factor kappa B kinase subunit epsilon in Human [GtoPdb: 2040] [UniProtKB: Q14164]
GtoPdb - - 8.7 pIC50 2 nM IC50 J Med Chem (2020) 63: 601-612 [PMID:31859507]
serine/threonine kinase 17a in Human [GtoPdb: 2214] [UniProtKB: Q9UEE5]
GtoPdb - - 6.51 pIC50 311 nM IC50 J Med Chem (2020) 63: 601-612 [PMID:31859507]
TANK binding kinase 1 in Human [GtoPdb: 2237] [UniProtKB: Q9UHD2]
GtoPdb Inhibition at low ATP concentration. - 8.7 pIC50 2 nM IC50 J Med Chem (2020) 63: 601-612 [PMID:31859507]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.