GPR15L [Ligand Id: 10567] activity data from GtoPdb

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  • GPR15 in Human [GtoPdb: 87] [UniProtKB: P49685]
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  • MRGPRX1 in Human [GtoPdb: 156] [UniProtKB: Q96LB2]
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  • MRGPRX2 in Human [GtoPdb: 157] [UniProtKB: Q96LB1]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GPR15 in Human [GtoPdb: 87] [UniProtKB: P49685]
GtoPdb Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin. - 5.85 pEC50 1400 nM EC50 Sci Signal (2017) 10: [PMID:28900043]
MRGPRX1 in Human [GtoPdb: 156] [UniProtKB: Q96LB2]
GtoPdb Determined in a FLIPR calcium imaging assay using HEK cells heterologously expressing hMRGPRX1 - 4.74 pEC50 18100 nM EC50 Sci Adv (2022) 8: eabm7342 [PMID:35704588]
MRGPRX2 in Human [GtoPdb: 157] [UniProtKB: Q96LB1]
GtoPdb Determined in a FLIPR calcium imaging assay using HEK cells heterologously expressing hMRGPRX2 - 5.72 pEC50 1900 nM EC50 Sci Adv (2022) 8: eabm7342 [PMID:35704588]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.