compound 16 [PMID: 31525966] [Ligand Id: 10501] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| perforin 1 in Human [GtoPdb: 3100] [UniProtKB: P14222] | ||||||||
| GtoPdb | Inhibition of perforin-mediated lysis of 51Cr-loaded K562 target cells in the presence of KHYG1 human NK cells. Measured as release of 51Cr. | - | 5.35 | pIC50 | 4430 | nM | IC50 | J Med Chem (2020) 63: 2229-2239 [PMID:31525966] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
