compound 16 [PMID: 31525966] [Ligand Id: 10501] activity data from GtoPdb

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  • perforin 1 in Human [GtoPdb: 3100] [UniProtKB: P14222]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
perforin 1 in Human [GtoPdb: 3100] [UniProtKB: P14222]
GtoPdb Inhibition of perforin-mediated lysis of 51Cr-loaded K562 target cells in the presence of KHYG1 human NK cells. Measured as release of 51Cr. - 5.35 pIC50 4430 nM IC50 J Med Chem (2020) 63: 2229-2239 [PMID:31525966]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.