ROCK inhibitor 3 [Ligand Id: 10425] activity data from GtoPdb

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  • Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
Created with Highcharts 10.3.3ValuesChart context menuRho associated coiled-coil containing protein kinase 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
Created with Highcharts 10.3.3ValuesChart context menuRho associated coiled-coil containing protein kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
GtoPdb - - 8 pIC50 10 nM IC50 Eur J Pharmacol (2019) 850: 126-134 [PMID:30753868]
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb - - 8.11 pIC50 7.8 nM IC50 Eur J Pharmacol (2019) 850: 126-134 [PMID:30753868]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.