PDE4 inhibitor 16 [Ligand Id: 10400] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499] | ||||||||
| GtoPdb | Inhibition of enzymatic activity of the recombinant human PDE4D catalytic domain in vitro. | - | 6.62 | pIC50 | 240 | nM | IC50 | J Med Chem (2019) 62: 5579-5593 [PMID:31099559] |
| phosphodiesterase 10A in Human [GtoPdb: 1310] [UniProtKB: Q9Y233] | ||||||||
| GtoPdb | Inhibition of enzymatic activity of the recombinant human PDE10A catalytic domain in vitro. | - | 6.04 | pIC50 | 920 | nM | IC50 | J Med Chem (2019) 62: 5579-5593 [PMID:31099559] |
| phosphodiesterase 6C in Human [GtoPdb: 1314] [UniProtKB: P51160] | ||||||||
| GtoPdb | Inhibition of enzymatic activity of the recombinant human PDE6C catalytic domain in vitro. | - | 5.48 | pIC50 | 3300 | nM | IC50 | J Med Chem (2019) 62: 5579-5593 [PMID:31099559] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
