NFP [Ligand Id: 10185] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143] | ||||||||
| GtoPdb | In a competitive radioligand membrane binding assay measuring displacement of [3H]diprenorphine by NFP from δ receptor expressed in CHO cells. | - | 6.8 | pKi | 157 | nM | Ki | J Med Chem (2019) 62: 561-574 [PMID:30608693] |
| κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145] | ||||||||
| GtoPdb | In a competitive radioligand membrane binding assay measuring displacement of [3H]diprenorphine by NFP from κ receptor expressed in CHO cells. | - | 8.32 | pKi | 4.8 | nM | Ki | J Med Chem (2019) 62: 561-574 [PMID:30608693] |
| μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372] | ||||||||
| GtoPdb | In a competitive radioligand membrane binding assay measuring displacement of [3H]naloxone by NFP from μ receptor expressed in CHO cells. | - | 9.44 | pKi | 0.36 | nM | Ki | J Med Chem (2019) 62: 561-574 [PMID:30608693] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
