ChEMBL ligand: CHEMBL1615281 (4-{[(4'-Fluorophenyl)Carbamoyl]Amino}Benzenesulfonamide, NSC-213841, Slc-0111, SLC0111, U-104)
carbonic anhydrase 1/Carbonic anhydrase I in Human [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 2/Carbonic anhydrase II in Human [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 4/Carbonic anhydrase IV in Human [ChEMBL: CHEMBL3729] [GtoPdb: 2599] [UniProtKB: P22748] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 9/Carbonic anhydrase IX in Human [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 7/Carbonic anhydrase VII in Human [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 12/Carbonic anhydrase XII in Human [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570] There should be some charts here, you may need to enable JavaScript!
PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) in Mycobacterium tuberculosis [ChEMBL: CHEMBL5767] [UniProtKB: P96878] There should be some charts here, you may need to enable JavaScript!
Uncharacterized protein Rv1284/MT1322 in Mycobacterium tuberculosis [ChEMBL: CHEMBL5631] [UniProtKB: P9WPJ7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
carbonic anhydrase 1/Carbonic anhydrase I in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915]
GtoPdb	-	-	5.29	pKi	5080	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3 [PMID:26233435]
ChEMBL	Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	J Med Chem (2011) 54: 1896-1902 [PMID:21361354]
ChEMBL	Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method	B	5.29	pKi	5080	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3853 [PMID:26233435]
ChEMBL	Inhibition of human carbonic anhydrase 1 for 15 mins by stopped flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	Bioorg Med Chem (2016) 24: 976-981 [PMID:26810836]
ChEMBL	Inhibition of human recombinant CA1 preincubated for 15 mins prior to testing by stopped flow CO2 hydrase assay	B	5.29	pKi	5080	nM	Ki	Bioorg Med Chem (2016) 24: 3043-3051 [PMID:27234893]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	Bioorg Med Chem (2017) 25: 2569-2576 [PMID:28347633]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay	B	5.29	pKi	5080	nM	Ki	Bioorg Med Chem (2017) 25: 3567-3573 [PMID:28522267]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	ACS Med Chem Lett (2017) 8: 963-968 [PMID:28947945]
ChEMBL	Inhibition of human CA1 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye based stopped-flow CO2 hydrase assay	B	5.29	pKi	5080	nM	Ki	J Med Chem (2018) 61: 6328-6338 [PMID:29962205]
ChEMBL	Inhibition of recombinant human CA1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	Eur J Med Chem (2019) 181: 111573-111573 [PMID:31394463]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	Bioorg Med Chem (2019) 27: 1588-1594 [PMID:30846402]
ChEMBL	Inhibition of human CA1 preincubated for 15 mins by stopped-flow carbon dioxide hydration assay	B	5.29	pKi	5080	nM	Ki	ACS Med Chem Lett (2020) 11: 1000-1005 [PMID:32435417]
ChEMBL	Inhibition of recombinant human CA1 pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	Eur J Med Chem (2021) 218: 113360-113360 [PMID:33773285]
ChEMBL	Inhibition of recombinant human CA1 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	J Med Chem (2021) 64: 3100-3114 [PMID:33721499]
ChEMBL	Inhibition of human CA1 measured after 15 mins by stopped flow carbon dioxide anhydrase assay	B	5.29	pKi	5080	nM	Ki	Eur J Med Chem (2021) 225: 113800-113800 [PMID:34482273]
ChEMBL	Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	Eur J Med Chem (2022) 228: 114008-114008 [PMID:34871842]
ChEMBL	Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	5.29	pKi	5080	nM	Ki	J Med Chem (2022) 65: 824-837 [PMID:34958217]
carbonic anhydrase 2/Carbonic anhydrase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918]
ChEMBL	Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	J Med Chem (2022) 65: 824-837 [PMID:34958217]
ChEMBL	Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	J Med Chem (2021) 64: 3100-3114 [PMID:33721499]
ChEMBL	Inhibition of human CA2 measured after 15 mins by stopped flow carbon dioxide anhydrase assay	B	6.02	pKi	960	nM	Ki	Eur J Med Chem (2021) 225: 113800-113800 [PMID:34482273]
ChEMBL	Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Eur J Med Chem (2022) 228: 114008-114008 [PMID:34871842]
ChEMBL	Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method	B	6.02	pKi	960	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3853 [PMID:26233435]
ChEMBL	Inhibition of human carbonic anhydrase 2 for 15 mins by stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Bioorg Med Chem (2016) 24: 976-981 [PMID:26810836]
ChEMBL	Inhibition of human recombinant CA2 preincubated for 15 mins prior to testing by stopped flow CO2 hydrase assay	B	6.02	pKi	960	nM	Ki	Bioorg Med Chem (2016) 24: 3043-3051 [PMID:27234893]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Bioorg Med Chem (2017) 25: 2569-2576 [PMID:28347633]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	ACS Med Chem Lett (2017) 8: 963-968 [PMID:28947945]
ChEMBL	Inhibition of human CA2 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye based stopped-flow CO2 hydrase assay	B	6.02	pKi	960	nM	Ki	J Med Chem (2018) 61: 6328-6338 [PMID:29962205]
ChEMBL	Inhibition of recombinant human CA2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Eur J Med Chem (2019) 181: 111573-111573 [PMID:31394463]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 2 by stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Eur J Med Chem (2019) 162: 147-160 [PMID:30445264]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Bioorg Med Chem (2019) 27: 1588-1594 [PMID:30846402]
ChEMBL	Inhibition of human CA2 preincubated for 15 mins by stopped-flow carbon dioxide hydration assay	B	6.02	pKi	960	nM	Ki	ACS Med Chem Lett (2020) 11: 1000-1005 [PMID:32435417]
ChEMBL	Inhibition of human CAH2 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	J Med Chem (2021) 64: 1713-1724 [PMID:33523653]
ChEMBL	Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydration assay	B	6.02	pKi	960	nM	Ki	Eur J Med Chem (2021) 218: 113360-113360 [PMID:33773285]
ChEMBL	Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assay	B	7.02	pKi	96	nM	Ki	J Med Chem (2011) 54: 1896-1902 [PMID:21361354]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay	B	7.02	pKi	96	nM	Ki	Bioorg Med Chem (2017) 25: 3567-3573 [PMID:28522267]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay	B	7.02	pKi	96	nM	Ki	Bioorg Med Chem Lett (2011) 21: 102-105 [PMID:21145236]
carbonic anhydrase 4/Carbonic anhydrase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3729] [GtoPdb: 2599] [UniProtKB: P22748]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 4 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	6.54	pKi	286	nM	Ki	ACS Med Chem Lett (2017) 8: 963-968 [PMID:28947945]
carbonic anhydrase 9/Carbonic anhydrase IX in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790]
ChEMBL	Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assay	B	7.35	pKi	45.1	nM	Ki	J Med Chem (2011) 54: 1896-1902 [PMID:21361354]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assay	B	7.35	pKi	45.1	nM	Ki	Eur J Med Chem (2016) 110: 259-266 [PMID:26840366]
ChEMBL	Inhibition of human CA9 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye based stopped-flow CO2 hydrase assay	B	7.35	pKi	45.1	nM	Ki	J Med Chem (2018) 61: 6328-6338 [PMID:29962205]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydration assay	B	7.35	pKi	45.1	nM	Ki	Bioorg Med Chem (2019) 27: 1588-1594 [PMID:30846402]
ChEMBL	Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	7.35	pKi	45.1	nM	Ki	J Med Chem (2022) 65: 824-837 [PMID:34958217]
ChEMBL	Inhibition of human recombinant CA9 preincubated for 15 mins prior to testing by stopped flow CO2 hydrase assay	B	7.35	pKi	45	nM	Ki	Bioorg Med Chem (2016) 24: 3043-3051 [PMID:27234893]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-9 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay	B	7.35	pKi	45	nM	Ki	Bioorg Med Chem (2017) 25: 3567-3573 [PMID:28522267]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 9 catalytic domain preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	ACS Med Chem Lett (2017) 8: 963-968 [PMID:28947945]
ChEMBL	Inhibition of human CA9 measured after 15 mins by stopped flow carbon dioxide anhydrase assay	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2021) 225: 113800-113800 [PMID:34482273]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2020) 185: 111843-111843 [PMID:31718943]
ChEMBL	Inhibition of recombinant human CA9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2019) 181: 111573-111573 [PMID:31394463]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 9 incubated for 1 hr prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	J Med Chem (2020) 63: 321-333 [PMID:31794211]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 9 by stopped flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2019) 162: 147-160 [PMID:30445264]
ChEMBL	Inhibition of carbonic anhydrase 9 (unknown origin)	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2019) 162: 147-160 [PMID:30445264]
ChEMBL	Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2022) 228: 114008-114008 [PMID:34871842]
ChEMBL	Inhibition of human CA9 preincubated for 15 mins by stopped-flow carbon dioxide hydration assay	B	7.35	pKi	45	nM	Ki	ACS Med Chem Lett (2020) 11: 1000-1005 [PMID:32435417]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	Bioorg Med Chem (2017) 25: 2569-2576 [PMID:28347633]
ChEMBL	Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration method	B	7.35	pKi	45	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3853 [PMID:26233435]
ChEMBL	Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	Bioorg Med Chem (2016) 24: 976-981 [PMID:26810836]
ChEMBL	Inhibition of recombinant human CA9 pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydration assay	B	7.35	pKi	45	nM	Ki	Eur J Med Chem (2021) 218: 113360-113360 [PMID:33773285]
GtoPdb	-	-	7.35	pKi	45	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3 [PMID:26233435]
ChEMBL	Inhibition of human CAH9 catalytic domain expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assay	B	9	pKi	1	nM	Ki	J Med Chem (2021) 64: 1713-1724 [PMID:33523653]
carbonic anhydrase 7/Carbonic anhydrase VII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-7 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay	B	5.07	pKi	8550	nM	Ki	Bioorg Med Chem (2017) 25: 3567-3573 [PMID:28522267]
ChEMBL	Inhibition of human CA7 preincubated for 15 mins by stopped-flow carbon dioxide hydration assay	B	5.07	pKi	8550	nM	Ki	ACS Med Chem Lett (2020) 11: 1000-1005 [PMID:32435417]
ChEMBL	Inhibition of recombinant human CA7 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay	B	5.07	pKi	8550	nM	Ki	J Med Chem (2021) 64: 3100-3114 [PMID:33721499]
carbonic anhydrase 12/Carbonic anhydrase XII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570]
ChEMBL	Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	J Med Chem (2011) 54: 1896-1902 [PMID:21361354]
ChEMBL	Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration method	B	8.35	pKi	4.5	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3853 [PMID:26233435]
ChEMBL	Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Bioorg Med Chem (2016) 24: 976-981 [PMID:26810836]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2016) 110: 259-266 [PMID:26840366]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Bioorg Med Chem (2017) 25: 2569-2576 [PMID:28347633]
ChEMBL	Inhibition of human CA12 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye based stopped-flow CO2 hydrase assay	B	8.35	pKi	4.5	nM	Ki	J Med Chem (2018) 61: 6328-6338 [PMID:29962205]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2020) 185: 111843-111843 [PMID:31718943]
ChEMBL	Inhibition of recombinant human CA12 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2019) 181: 111573-111573 [PMID:31394463]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 12 incubated for 1 hr prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	J Med Chem (2020) 63: 321-333 [PMID:31794211]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 12 by stopped flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2019) 162: 147-160 [PMID:30445264]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Bioorg Med Chem (2019) 27: 1588-1594 [PMID:30846402]
ChEMBL	Inhibition of human CA12 preincubated for 15 mins by stopped-flow carbon dioxide hydration assay	B	8.35	pKi	4.5	nM	Ki	ACS Med Chem Lett (2020) 11: 1000-1005 [PMID:32435417]
ChEMBL	Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2021) 218: 113360-113360 [PMID:33773285]
ChEMBL	Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	J Med Chem (2021) 64: 3100-3114 [PMID:33721499]
ChEMBL	Inhibition of human CA12 measured after 15 mins by stopped flow carbon dioxide anhydrase assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2021) 225: 113800-113800 [PMID:34482273]
ChEMBL	Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	Eur J Med Chem (2022) 228: 114008-114008 [PMID:34871842]
ChEMBL	Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay	B	8.35	pKi	4.5	nM	Ki	J Med Chem (2022) 65: 824-837 [PMID:34958217]
GtoPdb	-	-	8.35	pKi	4.5	nM	Ki	Bioorg Med Chem Lett (2015) 25: 3850-3 [PMID:26233435]
PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5767] [UniProtKB: P96878]
ChEMBL	Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assay	B	7.28	pKi	53	nM	Ki	Bioorg Med Chem Lett (2011) 21: 102-105 [PMID:21145236]
Uncharacterized protein Rv1284/MT1322 in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5631] [UniProtKB: P9WPJ7]
ChEMBL	Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assay	B	8.19	pKi	6.4	nM	Ki	Bioorg Med Chem Lett (2011) 21: 102-105 [PMID:21145236]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]