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Pentraxins

Overview

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The penrtaxin (a.k.a. pentaxin) family of proteins includes C reactive protein (CRP) [4], serum amyloid P component protein (SAP) and female protein (FP; a hamster homologue of SAP) [1], all of which are involved in acute immunological responses [2-3]. This family of proteins is characterised structurally by a discoid arrangement of five noncovalently bound subunits.

Subfamilies

Families that contain targets of relevance to immunopharmacology are highlighted in blue

References

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How to cite this family page

Database page citation:

Pentraxins. Accessed on 03/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=906.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.