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The pentaxin (aka pentraxin) family of proteins includes C reactive protein (CRP) [4], serum amyloid P component protein (SAP) and female protein (FP; a hamster homologue of SAP) [1], all of which are involved in acute immunological responses [2-3]. This family of proteins is characterised structurally by a discoid arrangement of five noncovalently bound subunits.


Families that contain targets of relevance to immunopharmacology are highlighted in blue


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How to cite this family page

Database page citation:

Pentaxins. Accessed on 24/10/2019. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Overview. Br J Pharmacol. 174 Suppl 1: S1-S16.