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Prostanoid receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Prostanoid Receptors [72]) are activated by the endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF, PGH2, prostacyclin [PGI2] and thromboxane A2. Measurement of the potency of PGI2 and thromboxane A2 is hampered by their instability in physiological salt solution; they are often replaced by cicaprost and U46619, respectively, in receptor characterization studies.

Receptors

Targets of relevance to immunopharmacology are highlighted in blue

DP1 receptor C Show summary » More detailed page

DP2 receptor C Show summary » More detailed page

EP1 receptor C Show summary » More detailed page

EP2 receptor C Show summary » More detailed page

EP3 receptor C Show summary » More detailed page

EP4 receptor C Show summary » More detailed page

FP receptor C Show summary » More detailed page

IP receptor C Show summary » More detailed page

TP receptor C Show summary » More detailed page

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors. Br J Pharmacol. 174 Suppl 1: S17-S129.