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Alpha subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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These two classical PKC isoforms are Ser/Thr kinases. They are activated by Ca2+ and diacylglycerol, and may be inhibited by GF109203X, calphostin C, Gö 6983, chelerythrine and Ro31-8220.


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Targets of relevance to immunopharmacology are highlighted in blue

PKCβ (protein kinase C beta) C Show summary » More detailed page go icon to follow link

PKCγ (protein kinase C gamma) C Show summary » More detailed page go icon to follow link


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How to cite this family page

Database page citation:

Alpha subfamily. Accessed on 20/04/2021. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.