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Alpha subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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These two classical PKC isoforms are Ser/Thr kinases. They are activated by Ca2+ and diacylglycerol, and may be inhibited by GF109203X, calphostin C, Gö 6983, chelerythrine and Ro31-8220.

Enzymes

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Targets of relevance to immunopharmacology are highlighted in blue

PKCβ (protein kinase C beta) C Show summary » More detailed page go icon to follow link

PKCγ (protein kinase C gamma) C Show summary » More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Alpha subfamily. Accessed on 30/09/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=532.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.