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N-Acylethanolamine turnover C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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N-acylethanolamine (NAE) is fatty acid amide that is required for the biosynthesis of bioactive lipid amide mediators of the endocannabinoid system.

Enzymes

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Targets of relevance to immunopharmacology are highlighted in blue

NAPE-PLD (N-Acylphosphatidylethanolamine-phospholipase D) C Show summary » More detailed page go icon to follow link

FAAH (Fatty acid amide hydrolase) C Show summary » More detailed page go icon to follow link

FAAH2 (Fatty acid amide hydrolase-2) C Show summary » More detailed page go icon to follow link

NAAA (N-Acylethanolamine acid amidase) C Show summary » More detailed page go icon to follow link

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References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.