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Dimethylarginine dimethylaminohydrolases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Dimethylarginine dimethylaminohydrolases (DDAH, EC 3.5.3.18) are cytoplasmic enzymes which hydrolyse NG,NG-dimethyl-L-arginine to form dimethylamine and L-citrulline.

Enzymes

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Targets of relevance to immunopharmacology are highlighted in blue

DDAH1 (NG,NG-Dimethylarginine dimethylaminohydrolase 1) C Show summary »

DDAH2 (NG,NG-Dimethylarginine dimethylaminohydrolase 2) C Show summary »

References

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How to cite this family page

Database page citation:

Dimethylarginine dimethylaminohydrolases. Accessed on 30/09/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=252.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.