Organic zwitterions/cation transporters (OCTN) C
Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
Overview
Organic zwitterions/cation transporters (OCTN) function as organic cation uniporters, organic cation/proton exchangers or sodium/L-carnitine co-transporters.
Transporters
Targets of relevance to immunopharmacology are highlighted in blue
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OCTN1 (Organic cation/carnitine transporter 1 / SLC22A4) C Show summary » |
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OCTN2 (Organic cation/carnitine transporter 2 / SLC22A5) C Show summary » |
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CT2 (Carnitine transporter 2 / SLC22A16) C Show summary » |
Comments
Further reading
How to cite this family page
Database page citation:
Bruno Hagenbuch. Organic zwitterions/cation transporters (OCTN). Accessed on 21/08/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=197.
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Transporters. Br J Pharmacol. 174 Suppl 1: S360-S446.
Mutations in the SLC22A5 gene lead to primary carnitine deficiency [1].