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SLC5 family of sodium-dependent glucose transporters C


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The SLC5 family of sodium-dependent glucose transporters includes, in mammals, the Na+/substrate co-transporters for glucose (e.g. choline), D-glucose, monocarboxylates, myo-inositol and I- [2-5]. Members of the SLC5 and SLC6 families, along with other unrelated Na+ cotransporters (i.e. Mhp1 and BetP), share a common structural core that contains an inverted repeat of 5TM α-helical domains [1].


Families that contain targets of relevance to immunopharmacology are highlighted in blue

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How to cite this family page

Database page citation:

SLC5 family of sodium-dependent glucose transporters. Accessed on 17/10/2019. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Transporters. Br J Pharmacol. 174 Suppl 1: S360-S446.