Top ▲

Basic leucine zipper domain TFs

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


Click here for help

« Hide

This is a family of structurally divergent basic leucine zipper (bZIP) transcription factors (curated by HGNC in the Basic leucine zipper proteins gene group). The family includes the FOS, JUN, CREB, ATF, MAF and NF subgroups of transcription factors.


Click here for help

Targets of relevance to immunopharmacology are highlighted in blue

NRF2 (nuclear factor, erythroid 2 like 2) Show summary » More detailed page go icon to follow link

How to cite this family page

Database page citation:

Basic leucine zipper domain TFs. Accessed on 23/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets. Br J Pharmacol. 180 Suppl 2:S1-22.