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Basic leucine zipper domain TFs

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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This is a family of structurally divergent basic leucine zipper (bZIP) transcription factors (curated by HGNC in the Basic leucine zipper proteins gene group). The family includes the FOS, JUN, CREB, ATF, MAF and NF subgroups of transcription factors.


Targets of relevance to immunopharmacology are highlighted in blue

NRF2 (nuclear factor, erythroid 2 like 2) Show summary » More detailed page

How to cite this family page

Database page citation:

Basic leucine zipper domain TFs. Accessed on 24/10/2019. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Overview. Br J Pharmacol. 174 Suppl 1: S1-S16.