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lysine acetyltransferase 2A

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Target not currently curated in GtoImmuPdb

Target id: 2736

Nomenclature: lysine acetyltransferase 2A

Family: 2.3.1.48 Histone acetyltransferases (HATs)

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 837 17q21.2 KAT2A lysine acetyltransferase 2A
Mouse - 830 11 63.53 cM Kat2a K(lysine) acetyltransferase 2A
Rat - 832 10q32.1 Kat2a lysine acetyltransferase 2A
Previous and Unofficial Names Click here for help
PCAF-b | GCN5L2 | K(lysine) acetyltransferase 2A
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Immuno Process Associations
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 2 GO processes
GO:0045589 regulation of regulatory T cell differentiation ISS
GO:0050863 regulation of T cell activation ISS
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 2 GO processes
GO:0001819 positive regulation of cytokine production ISS
click arrow to show/hide IEA associations
GO:0071356 cellular response to tumor necrosis factor IEA
Immuno Process:  Immune regulation
GO Annotations:  Associated to 2 GO processes
GO:0045589 regulation of regulatory T cell differentiation ISS
GO:0050863 regulation of T cell activation ISS
Immuno Process:  Immune system development
GO Annotations:  Associated to 1 GO processes
GO:0045589 regulation of regulatory T cell differentiation ISS
Immuno Process:  T cell (activation)
GO Annotations:  Associated to 2 GO processes
GO:0045589 regulation of regulatory T cell differentiation ISS
GO:0050863 regulation of T cell activation ISS
General Comments
This is a bromo-domain containing protein involved in chromatin modification.

How to cite this page

2.3.1.48 Histone acetyltransferases (HATs): lysine acetyltransferase 2A. Last modified on 30/03/2016. Accessed on 01/07/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2736.