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3-ketodihydrosphingosine reductase

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

2463
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3-ketodihydrosphingosine reductase Show summary »

Target Id 2463
Nomenclature 3-ketodihydrosphingosine reductase
Previous and unofficial names 3-dehydrosphinganine reductase | DHSR, SDR35C1 | FVT1 | KDS reductase
Genes KDSR (Hs), Kdsr (Mm), Kdsr (Rn)
Ensembl ID ENSG00000119537 (Hs), ENSMUSG00000009905 (Mm), ENSRNOG00000002781 (Rn)
UniProtKB AC Q06136 (Hs), Q6GV12 (Mm), D3Z9P1 (Rn)
EC number
1.1.1.102 3-Ketosphinganine + NADPH -> NADP+ + dihydrosphingosine
Cofactors
NADPH

How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.