Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	1061	19q13.42	NLRP12	NLR family pyrin domain containing 12
Mouse	-	1054	7 A1	Nlrp12	NLR family, pyrin domain containing 12
Rat	-	-	1q12	Nlrp12	NLR family, pyrin domain containing 12

Previous and Unofficial Names

CLR19.3 | NALP12 | PAN6 | PYPAF7 | RNO2 | NACHT, leucine rich repeat and PYD containing 12 | Monarch1 | FCAS2 | RNO | NLR family | NLR family, pyrin domain containing 12

Database Links
Alphafold	P59046 (Hs), E9Q5R7 (Mm)
Ensembl Gene	ENSG00000142405 (Hs), ENSMUSG00000078817 (Mm), ENSRNOG00000060745 (Rn)
Entrez Gene	91662 (Hs), 378425 (Mm), 292541 (Rn)
Human Protein Atlas	ENSG00000142405 (Hs)
KEGG Gene	hsa:91662 (Hs), mmu:378425 (Mm), rno:292541 (Rn)
OMIM	609648 (Hs)
Pharos	P59046 (Hs)
UniProtKB	P59046 (Hs), E9Q5R7 (Mm)
Wikipedia	NLRP12 (Hs)

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Immune regulation

Immuno Process:  Cytokine production & signalling

Immuno Process:  Chemotaxis & migration

Physiological Functions Comments

Involved in inflammasome formation, bacterial control and inflammatory migration.

Clinically-Relevant Mutations and Pathophysiology
Disease:  Dermatitis Description: Includes atopic, seborrhoeic, and contact dermatitis. Disease Ontology: DOID:2723
Disease:  Familial cold autoinflammatory syndrome 2; FCAS2 Synonyms: NLRP12-associated hereditary periodic fever syndrome [Orphanet: ORPHA247868] OMIM: 611762 Orphanet: ORPHA247868