Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	1062	19q13.42	NLRP2	NLR family pyrin domain containing 2
Mouse	-	-	7 3.07 cM	Nlrp2	NLR family, pyrin domain containing 2

Previous and Unofficial Names

CLR19.9 | NALP2 | NBS1 | PAN1 | PYPAF2 | NACHT, leucine rich repeat and PYD containing 2 | XXbac-BPG230H20.8 | NLR family, pyrin domain containing 2 | NLR family

Database Links
Alphafold	Q9NX02 (Hs)
CATH/Gene3D	3.80.10.10
Ensembl Gene	ENSG00000022556 (Hs), ENSMUSG00000035177 (Mm)
Entrez Gene	55655 (Hs), 232827 (Mm)
Human Protein Atlas	ENSG00000022556 (Hs)
KEGG Gene	hsa:55655 (Hs), mmu:232827 (Mm)
OMIM	609364 (Hs)
Pharos	Q9NX02 (Hs)
UniProtKB	Q9NX02 (Hs)
Wikipedia	NLRP2 (Hs)

Immuno Process Associations

Immuno Process:  Cytokine production & signalling GO Annotations:  Associated to 2 GO processes GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IBA GO:0032731 positive regulation of interleukin-1 beta production IDA

Immuno Process:  Inflammation GO Annotations:  Associated to 3 GO processes, IEA only GO:0050727 regulation of inflammatory response IBA click arrow to show/hide IEA associations GO:0006954 inflammatory response IEA GO:0045087 innate immune response IEA

Physiological Functions Comments

Involved in embryonic development.

Clinically-Relevant Mutations and Pathophysiology
Disease:  Beckwith-Wiedemann syndrome Disease Ontology: DOID:5572 OMIM: 130650 Orphanet: ORPHA116
Disease:  Recurrent miscarriage