Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	975	11q23.3	NLRX1	NLR family member X1
Mouse	-	975	9 A5.2	Nlrx1	NLR family member X1
Rat	-	973	8q22	Nlrx1	NLR family member X1

Previous and Unofficial Names

CLR11.3 | NOD9 | NOD-like receptor X1 | NLR family member X1 | DLNB26 | NOD26 | NOD5

Database Links
Alphafold	Q86UT6 (Hs), Q3TL44 (Mm), Q5FVQ8 (Rn)
Ensembl Gene	ENSG00000160703 (Hs), ENSMUSG00000032109 (Mm), ENSRNOG00000052386 (Rn)
Entrez Gene	79671 (Hs), 270151 (Mm), 315599 (Rn)
Human Protein Atlas	ENSG00000160703 (Hs)
KEGG Gene	hsa:79671 (Hs), mmu:270151 (Mm), rno:315599 (Rn)
OMIM	611947 (Hs)
Pharos	Q86UT6 (Hs)
UniProtKB	Q86UT6 (Hs), Q3TL44 (Mm), Q5FVQ8 (Rn)
Wikipedia	NLRX1 (Hs)

Immunopharmacology Comments

NLRX1 is an intracellular pattern recognition receptor that plays a role in host immunity to certain bacterial infections.

Immuno Process Associations

Immuno Process:  Cytokine production & signalling GO Annotations:  Associated to 4 GO processes click arrow to show/hide IEA associations GO:0010936 negative regulation of macrophage cytokine production IEA GO:0032688 negative regulation of interferon-beta production IEA GO:0032715 negative regulation of interleukin-6 production IEA GO:0039536 negative regulation of RIG-I signaling pathway IEA

Immuno Process:  Inflammation GO Annotations:  Associated to 4 GO processes, IEA only click arrow to show/hide IEA associations GO:0039536 negative regulation of RIG-I signaling pathway IEA GO:0045087 innate immune response IEA GO:0045824 negative regulation of innate immune response IEA GO:0050728 negative regulation of inflammatory response IEA

Immuno Process:  Immune regulation GO Annotations:  Associated to 4 GO processes, IEA only click arrow to show/hide IEA associations GO:0010936 negative regulation of macrophage cytokine production IEA GO:0039536 negative regulation of RIG-I signaling pathway IEA GO:0045824 negative regulation of innate immune response IEA GO:0050728 negative regulation of inflammatory response IEA

Immuno Process:  Cellular signalling GO Annotations:  Associated to 1 GO processes, IEA only click arrow to show/hide IEA associations GO:0039536 negative regulation of RIG-I signaling pathway IEA

Physiological Functions Comments

Involved in negative regulation of inflammatory signalling.