Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	967	21q21.3	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif 1
Mouse	-	968	16 48.2 cM	Adamts1	ADAM metallopeptidase with thrombospondin type 1 motif 1
Rat	-	967	11q11	Adamts1	ADAM metallopeptidase with thrombospondin type 1 motif, 1

Previous and Unofficial Names

C3-C5 | METH1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | ADAM metallopeptidase with thrombospondin type 1 motif | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif | ADAM metallopeptidase with thrombospondin type 1 motif 1

Database Links
Specialist databases
MEROPS	M12.222 (Hs)
Other databases
Alphafold	Q9UHI8 (Hs), P97857 (Mm), Q9WUQ1 (Rn)
BRENDA	3.4.24.-
CATH/Gene3D	2.20.100.10, 3.40.390.10
ChEMBL Target	CHEMBL5133 (Hs)
Ensembl Gene	ENSG00000154734 (Hs), ENSMUSG00000022893 (Mm), ENSRNOG00000001607 (Rn)
Entrez Gene	9510 (Hs), 11504 (Mm), 79252 (Rn)
Human Protein Atlas	ENSG00000154734 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:9510 (Hs), mmu:11504 (Mm), rno:79252 (Rn)
OMIM	605174 (Hs)
Pharos	Q9UHI8 (Hs)
RefSeq Nucleotide	NM_006988 (Hs), NM_009621 (Mm), NM_024400 (Rn)
RefSeq Protein	NP_008919 (Hs), NP_033751 (Mm), NP_077376 (Rn)
UniProtKB	Q9UHI8 (Hs), P97857 (Mm), Q9WUQ1 (Rn)
Wikipedia	ADAMTS1 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 12c [PMID: 16516466] Hs Inhibition 6.1 pKi 1 ⤷ pKi 6.1 (Ki 7.76x10-7 M) [1]